DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies
Figure 2
Kinetics of binding of Pt compounds to plasmid DNA. The Pt compounds are: (a) cisplatin with the initial ratios in the solution of 20 : 1, (b) 200 : 1, and (c) carboplatin with the initial ratios of 40 : 1 and (d) 200 : 1. The curves show the quantity of bound Pt compounds per DNA molecule at different incubation times at 25°C. Data in (a)–(d) are means from three measurements; error bars show standard deviations. The continuous black lines are exponential fits to the data.
