Evaluation of DNA Binding, Cleavage, and Cytotoxic Activity of Cu(II), Co(II), and Ni(II) Schiff Base Complexes of 1-Phenylindoline-2,3-dione with Isonicotinohydrazide

Table 1

Composition and physical characteristics of ligand and their complexes.

Ligand/; complexes	Molecular; formula	Color	Found (calculated) %				M.P; (°C)	Yield; (%)	Ω; (Ohm^−1 cm^2 M^−1)
			M	C	H	N
L	C20H14N4O2	Crystalline yellow		70.01; (70.14)	3.97; (4.12)	16.52; (16.37)	180	95	—
L–Cu	C41H31N8O4Cl2Cu	Green	7.51; (7.62)	59.37; (59.03)	3.71; (3.75)	13.11; (13.43)	>300	83	22.000
L–Co	C41H31N8O4Cl2Co	Dark green	6.58; (7.10)	59.32; (59.36)	3.63; (3.77)	13.47; (13.51)	>285	80	34.40
L–Ni	C41H31N8O4Cl2Ni	Yellow	7.31; (7.08)	59.35; (59.38)	3.68; (3.77)	13.56; (13.51)	>285	80	28.50