Table of Contents Author Guidelines Submit a Manuscript
Bioinorganic Chemistry and Applications
Volume 2014, Article ID 276598, 10 pages
http://dx.doi.org/10.1155/2014/276598
Research Article

Novel Zinc(II) Complexes of Heterocyclic Ligands as Antimicrobial Agents: Synthesis, Characterisation, and Antimicrobial Studies

1Department of Chemistry, Chikitsak Samuha’s Patkar-Varde College of Arts, Science and Commerce, Goregaon (W), Mumbai 400 062, India
2P. G. Department of Chemistry, Government of Maharashtra, Ismail Yusuf Arts, Science and Commerce College, Jogeshwari (East), Mumbai 400 060, India

Received 3 October 2013; Revised 10 December 2013; Accepted 26 December 2013; Published 23 February 2014

Academic Editor: Giovanni Natile

Copyright © 2014 Ramesh S. Yamgar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. “Antibiotic Resistance Questions & Answers”, Get Smart: Know When Antibiotics Work, Center for Disease Control and Prevention, Atlanta, Ga, USA, 2013.
  2. C. A. Lipinski, “Lead- and drug-like compounds: the rule-of-five revolution,” Drug Discovery Today: Technologies, vol. 1, no. 4, pp. 337–341, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. M. J. Macielag, “Chemical properties of antibacterials and their uniqueness,” in Antibiotic Discovery and Development, T. J. Dougherty and M. J. Pucci, Eds., pp. 801–802, 2012. View at Google Scholar
  4. D. F. Veber, S. R. Johnson, H.-Y. Cheng, B. R. Smith, K. W. Ward, and K. D. Kopple, “Molecular properties that influence the oral bioavailability of drug candidates,” Journal of Medicinal Chemistry, vol. 45, no. 12, pp. 2615–2623, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. M. M. R. Arkin and J. A. Wells, “Small-molecule inhibitors of protein-protein interactions: progressing towards the dream,” Nature Reviews Drug Discovery, vol. 3, no. 4, pp. 301–317, 2004. View at Google Scholar · View at Scopus
  6. M. Rizzotto, “Metal complexes as antimicrobial agents,” 2013, http://www.intechopen.com/download/pdf/39255.
  7. A. M. Elsome, J. M. T. Hamilton-Miller, W. Brumfitt, and W. C. Noble, “Antimicrobial activities in vitro and in vivo of transition element complexes containing gold(I) and osmium(VI),” Journal of Antimicrobial Chemotherapy, vol. 37, no. 5, pp. 911–918, 1996. View at Publisher · View at Google Scholar · View at Scopus
  8. C. A. Ferguson, R. G. E. Murray, and P. Lancy Jr., “Effects of some platinum IV complexes on cell division of Escherichia coli,” Canadian Journal of Microbiology, vol. 25, no. 5, pp. 545–559, 1979. View at Google Scholar · View at Scopus
  9. R. B. Thurman and C. P. Gerba, “The molecular mechanisms of copper and silver ion disinfection of bacteria and viruses,” Critical Reviews in Environmental Control, vol. 18, no. 4, pp. 295–315, 1988. View at Google Scholar · View at Scopus
  10. B. Rosenberg, E. Renshaw, L. Vancamp, J. Hartwick, and J. Drobnik, “Platinum-induced filamentous growth in Escherichia coli,” Journal of Bacteriology, vol. 93, no. 2, pp. 716–721, 1967. View at Google Scholar · View at Scopus
  11. A. M. Elsome, W. Brumfitt, J. M. T. Hamilton-Miller, P. D. Savage, R. O. King, and S. Frickcr, “Antimicrobial activity and potential therapeutic use of new gold coordination complexes,” in Program and Abstracts of the 31st Interscience Conference on Anti-Microbial Agents and Chemotherapy, American Society for Microbiology, Chicago, Ill, USA, abstract 387, 1991.
  12. V. Pawar, S. V. Chavan, R. S. Yamgar et al., “Synthesis and characterization of novel transition metal complexes of 4-methyl-7-hydroxy 8-formyl coumarin and their biological activities,” Asian Journal of Research in Chemistry, vol. 4, no. 8, pp. 1238–1242, 2011. View at Google Scholar
  13. M. Mustapha, B. R. Thorat, S. Sawant, R. G. Atram, and R. Yamgar, “Synthesis of novel schiff bases and its transition metal complexes,” Journal of Chemical and Pharmaceutical Research, vol. 3, no. 4, pp. 5–9, 2011. View at Google Scholar · View at Scopus
  14. S. S. Sawant, V. Pawar, S. Janrao, S. R. Yamgar, and Y. Nivid, “Synthesis characterization of transition metal complexes of novel schiff base 8-[(z)-{[3-(N-methylamino)propyl]imino}methyl]-7-hydroxy-4-methyl-2h-chromen-2-one][NMAPIMHMC] and their biological activities,” International Journal of Research in Pharmacy and Chemistry, vol. 3, no. 3, pp. 636–644, 2013. View at Google Scholar
  15. A. I. Vogel, A. R. Tatchell, B. S. Furnis, A. J. Hannaford, and P. W. G. Smith, Vogel's Text Book of Practical Organic Chemistry, ELBS, 5th edition, 1996.
  16. A. Kulkarni, S. A. Patil, and P. S. Badami, “Synthesis, characterization, DNA cleavage and in vitro antimicrobial studies of La(III), Th(IV) and VO(IV) complexes with Schiff bases of coumarin derivatives,” European Journal of Medicinal Chemistry, vol. 44, no. 7, pp. 2904–2912, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. G. B. Bagihalli, P. G. Avaji, P. S. Badami, and S. A. Patil, “Synthesis, spectral characterization, electrochemical and biological studies of Co(II), Ni(II) and Cu(II) complexes with thiocarbohydrazone,” Journal of Coordination Chemistry, vol. 61, no. 17, pp. 2793–2806, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Baker, V. G. Matassa, and L. J. Street, “Imidazole, triazole and tetrazole derivatives,” patent no. US5602162 of Merck Sharp & Dohme Ltd.
  19. P. Rajnikant, “A process for the purification of (S)-4-((3-(dimethylamino)ethyl)-1H-indol-5yl)-methyl)-2-oxazolidinone,” European patent no. EP1227095B1 of Astrazeneca AB ,1996.
  20. L. J. Bellamy, The Infrared Spectra of Complex Molecules, Chapman and Hall, London, UK, 1980.
  21. K. Nakamoto, Infrared Spectra and Raman Spectra of Inorganic and Coordination Compounds, Wiley & Sons, New York, NY, USA, 1997.
  22. R. Schwalbe, L. Steele-Moore, and A. C. Goodwin, Antimicrobial Susceptibility Testing Protocols, CRC Press, 2007.
  23. B. G. Tweedy, “Possible mechanism for reduction of elemental sulfur by monilinia fructicola,” Phytopathology, vol. 55, pp. 910–914, 1964. View at Google Scholar
  24. A. K. Král'ová, K. Kissová, O. Švajlenová, and J. Vančo, “Biological activity of copper(II) N-salicylideneaminoacidato complexes. Reduction of chlorophyll content in freshwater alga Chlorella vulgaris and inhibition of photosynthetic electron transport in spinach chloroplasts,” Chemical Papers, vol. 58, no. 5, pp. 357–361, 2004. View at Google Scholar · View at Scopus
  25. J. Parekh, P. Inamdhar, R. Nair, S. Baluja, and S. Chanda, “Synthesis and antibacterial activity of some Schiff bases derived from 4-aminobenzoic acid,” Journal of the Serbian Chemical Society, vol. 70, no. 10, pp. 1155–1161, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. Y. Vaghasia, R. Nair, M. Soni, S. Baluja, and S. Chanda, “Synthesis, structural determination and antibacterial activity of compounds derived from vanillin and 4-aminoantipyrine,” Journal of the Serbian Chemical Society, vol. 69, no. 12, pp. 991–998, 2004. View at Publisher · View at Google Scholar
  27. N. Raman, “Antibacterial study of the mannich base, N-(1-morpholino-benzyl) semicarbazide and its transition metal(II) complexes,” Research Journal of Chemistry and Environment, vol. 4, p. 9, 2005. View at Google Scholar
  28. U. Galm, S. Heller, S. Shapiro, M. Page, S.-M. Li, and L. Heide, “Antimicrobial and DNA gyrase-inhibitory activities of novel clorobiocin derivatives produced by mutasynthesis,” Antimicrobial Agents and Chemotherapy, vol. 48, no. 4, pp. 1307–1312, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. E. J. Alvarez, V. H. Vartanian, and J. S. Brodbelt, “Metal complexation reactions of quinolone antibiotics in a quadrupole ion trap,” Analytical Chemistry, vol. 69, no. 6, pp. 1147–1155, 1997. View at Publisher · View at Google Scholar · View at Scopus