Synthesis, Characterization, Antimicrobial, DNA Cleavage, and In Vitro Cytotoxic Studies of Some Metal Complexes of Schiff Base Ligand Derived from Thiazole and Quinoline Moiety
Table 1
Physical, Analytical and Molar conductance data of Schiff base ligand (L) and its metal complexes.
Compound
M.W.a
M.P. (°C)b
Elemental Analysis, found (Calc.) %
(cm2 )
(BM)
Color
M
C
H
N
Cl
C20H15N5OS2
405
298
—
59.18 (59.25)
3.73 (3.70)
17.21 (17.28)
—
—
—
Yellow
Cu(C20H15N5OS2)(Cl2)
539.44
>320
11.79 (11.77)
44.41 (44.49)
2.80 (2.78)
12.93 (12.97)
13.17 (13.14)
50
1.73
Green
Co(C20H15N5OS2)(Cl2)
534.83
>324
11.09 (11.01)
44.95 (44.87)
2.82 (2.80)
13.15 (13.08)
13.21 (13.25)
61
4.31
Brown
Ni(C20H15N5OS2)(Cl2)
534.59
>320
10.92 (10.97)
44.85 (44.89)
2.75 (2.80)
13.12 (13.09)
13.30 (13.26)
56
2.78
Brown
Zn(C20H15N5OS2)(Cl2)
541.30
>310
12.03 (12.08)
44.39 (44.33)
2.72 (2.77)
12.92 (12.93)
13.15 (13.09)
55
Orange Yellow
Molecular weight of the compounds. Melting point of the compounds at their decomposition. Diamagnetic.