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Bioinorganic Chemistry and Applications
Volume 2014 (2014), Article ID 926287, 17 pages
http://dx.doi.org/10.1155/2014/926287
Research Article

Transition Metal(II) Complexes with Cefotaxime-Derived Schiff Base: Synthesis, Characterization, and Antimicrobial Studies

1Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Craiova, 107I Calea Bucureşti, 200478 Craiova, Romania
2Department of Microbiology, Faculty of Biology, University of Bucharest, 1-4 Aleea Portocalelor, 60101 Bucharest, Romania
3Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 66, 1 May Street, 200638 Craiova, Romania

Received 7 October 2013; Revised 23 December 2013; Accepted 27 December 2013; Published 12 February 2014

Academic Editor: Claudio Pettinari

Copyright © 2014 Aurora Reiss et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N.-X. Chin, J.-W. Gu, W. Fang, and H. C. Neu, “In vitro activity and β-lactamase stability of GR69153, a new long-acting cephalosporin,” Antimicrobial Agents and Chemotherapy, vol. 35, no. 2, pp. 259–266, 1991. View at Google Scholar · View at Scopus
  2. K. P. Fu, B. D. Foleno, S. C. Lafredo, J. M. LoCoco, and D. M. Isaacson, “In vitro and in vivo antibacterial activities of FK037, a novel parenteral broad-spectrum cephalosporin,” Antimicrobial Agents and Chemotherapy, vol. 37, no. 2, pp. 301–307, 1993. View at Google Scholar · View at Scopus
  3. J. R. Anacona and J. Estacio, “Synthesis and antibacterial activity of cefixime metal complexes,” Transition Metal Chemistry, vol. 31, no. 2, pp. 227–231, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. J. R. Anacona and J. J. Santaella, “In vitro, antibacterial activity of metal complexes containing a cephaclor derivative ligand,” Latin American Journal of Pharmacy, vol. 32, no. 1, pp. 101–106, 2013. View at Google Scholar
  5. J. R. Anacona and M. Lopez, “Mixed-ligand nickel(II) complexes containing sulfathiazole and cephalosporin antibiotics synthesis, characterization, and antibacterial activity,” International Journal of Inorganic Chemistry, vol. 2012, Article ID 106187, 8 pages, 2012. View at Google Scholar
  6. K. Singh, Y. Kumar, P. Puri, and G. Singh, “Spectroscopic, thermal, and antimicrobial studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes derived from bidentate ligands containing N and S donor atoms,” Bioinorganic Chemistry and Applications, vol. 2012, Article ID 729708, 9 pages, 2012. View at Publisher · View at Google Scholar
  7. M. R. Karekal, V. Biradar, and M. B. H. Mathada, “Synthesis, characterization, antimicrobial, DNA cleavage, and antioxidant studies of some metal complexes derived from Schiff base containing indole and quinoline moieties,” Bioinorganic Chemistry and Applications, vol. 2013, Article ID 315972, 16 pages, 2013. View at Publisher · View at Google Scholar
  8. K. M. Khan, M. Khan, M. Ali et al., “Superoxide respiratory burst inhibitory activity of Bis-schiff bases of isatins,” Journal of Chemical Society of Pakistan, vol. 35, no. 3, pp. 987–993, 2013. View at Google Scholar
  9. K. M. Khan, M. Taha, F. Rahim et al., “Acylhydrazide schiff bases: synthesis and antiglycation activity,” Journal of Chemical Society of Pakistan, vol. 35, no. 3, pp. 929–937, 2013. View at Google Scholar
  10. Q. B. Li, L. W. Xue, W. C. Yang, and G. Q. Zhao, “Two new schiff base NiII and CuII complexes: synthesis and structures,” Journal of the Chilian Chemical Society, vol. 58, no. 3, pp. 1880–1883, 2013. View at Google Scholar
  11. J. R. Anacona and C. Patiño, “Metalloantibiotics: synthesis and antibacterial activity of ceftazidime metal complexes,” Journal of Coordination Chemistry, vol. 62, no. 4, pp. 613–621, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. A. E. Ali, “Synthesis, spectral, thermal and antimicrobial studies of some new tri metallic biologically active ceftriaxone complexes,” Spectrochimica Acta A, vol. 78, no. 1, pp. 224–230, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. N. Raman, S. Sobha, and L. Mitu, “Design, synthesis, DNA binding ability, chemical nuclease activity and antimicrobial evaluation of Cu(II), Co(II), Ni(II) and Zn(II) metal complexes containing tridentate Schiff base,” Journal of Saudi Chemical Society, vol. 17, no. 2, pp. 151–159, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. N. Sultana, M. S. Arayne, and M. Afzal, “Synthesis and antibacterial activity of cephradine metal complexes: part II complexes with cobalt, copper, zinc and cadmium,” Pakistan Journal of Pharmaceutical Sciences, vol. 18, no. 1, pp. 36–42, 2005. View at Google Scholar · View at Scopus
  15. A. Sakthivel, N. Raman, and L. Mitu, “DNA interaction studies of pyrazolone and diimine incorporated Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes: synthesis, spectroscopic characterization and antimicrobial study,” Monatshefte Fur Chemie—Chemical Monthly, vol. 144, no. 5, pp. 605–620, 2013. View at Google Scholar
  16. Z. H. Chohan and C. T. Supuran, “In-vitro antibacterial and cytotoxic activity of cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes of the antibiotic drug cephalothin (keflin),” Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 20, no. 5, pp. 463–468, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. Z. H. Chohan, H. Pervez, K. M. Khan, A. Rauf, G. M. Maharvi, and C. T. Supuran, “Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins,” Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 19, no. 1, pp. 85–90, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. M. S. Iqbal, I. H. Bukhari, and M. Arif, “Preparation, characterization and biological evaluation of copper(II) and zinc(II) complexes with Schiff bases derived from amoxicillin and cephalexin,” Applied Organometallic Chemistry, vol. 19, no. 7, pp. 864–869, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. I. H. Bukhari, M. Arif, I. Akbar, and A. H. Khan, “Preparation, characterization and biological evaluation of Schiff base transition metal complexes with cephradine,” Pakistan Journal of Biological Sciences, vol. 8, no. 4, pp. 614–617, 2005. View at Google Scholar
  20. M. Arif, M. M. R. Qurashi, and M. A. Shad, “Metal-based antibacterial agents: synthesis, characterization, and in vitro biological evaluation of cefixime-derived Schiff bases and their complexes with Zn(II), Cu(II), Ni(II), and Co(II),” Journal of Coordination Chemistry, vol. 64, no. 11, pp. 1914–1930, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Joshi, V. Pawar, and V. Uma, “Antibacterial and antioxidant properties of Mn (II), Co (II), Ni (II) and Zn (II) complex of Schiff base derived from cephalexin,” Research Journal of Pharmaceutical, Biological and Chemical Sciences, vol. 2, no. 1, pp. 61–70, 2011. View at Google Scholar · View at Scopus
  22. J. R. Anacona, J. Calvo, and O. A. Almanza, “Synthesis, spectroscopic, and magnetic studies of mono- and polynuclear Schiff base metal complexes containing salicylidene-cefotaxime ligand,” International Journal of Inorganic Chemistry, vol. 2013, Article ID 108740, 7 pages, 2013. View at Publisher · View at Google Scholar
  23. C. Limban and M. C. Chifiriuc, “Antibacterial activity of new dibenzoxepinone oximes with fluorine and trifluoromethyl group substituents,” International Journal of Molecular Sciences, vol. 12, no. 10, pp. 6432–6444, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. C. Limban, A. V. Missir, I. C. Chirita et al., “Synthesis and antimicrobial properties of new 2-((4-ethylphenoxy)methyl) benzoylthioureas,” Chemical Papers, vol. 65, no. 1, pp. 60–69, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. C. Limban, L. Marutescu, and M. C. Chifiriuc, “Synthesis, spectroscopic properties and antipathogenic activity of new thiourea derivatives,” Molecules, vol. 16, no. 9, pp. 7593–7607, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. R. Olar, M. Badea, D. Marinescu et al., “Prospects for new antimicrobials based on N,N-dimethylbiguanide complexes as effective agents on both planktonic and adhered microbial strains,” European Journal of Medicinal Chemistry, vol. 45, no. 7, pp. 2868–2875, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. G. M. Nitulescu, C. Draghici, M. C. Chifiriuc, L. Marutescu, C. Bleotu, and A. V. Missir, “Synthesis and antimicrobial screening of N-(1-methyl-1Hpyrazole- 4-carbonyl)-thiourea derivatives,” Medicinal Chemistry Research, vol. 21, pp. 308–314, 2012. View at Google Scholar
  28. W. J. Geary, “The use of conductivity measurements in organic solvents for the characterisation of coordination compounds,” Coordination Chemistry Reviews, vol. 7, no. 1, pp. 81–122, 1971. View at Google Scholar · View at Scopus
  29. G. Brătulescu, Introduction in Organic Compounds Spectroscopy, Sitech, Craiova, Romania, 2009.
  30. K. Nakamoto, Infrared Spectra of Inorganic and Coordination Compounds, John Wiley & Sons, New York, NY, USA, 4th edition, 1986.
  31. G. Socrates, Infrared Characteristic Group Frequencies, John Wiley & Sons, Chichester, UK, 1980.
  32. A. B. P. Lever, Inorganic Spectroscopy, Elsevier, Amsterdam, The Netherlands, 2nd edition, 1984.
  33. E. König, “The Nephelauxetic Effect,” Structure and Bonding, vol. 9, pp. 175–212, 1971. View at Google Scholar
  34. F. A. Cotton, G. Williknson, C. A. Murillo, and M. Bochman, Advanced Inorganic Chemistry, John Wiley & Sons, New York, NY, USA, 6th edition, 2003.
  35. B. N. Figgis, Introduction to Ligand Fields, John Wiley & Sons, New York, NY, USA, 1976.
  36. N. Raman, R. Jeyamurugan, S. Sudharsan, K. Karuppasamy, and L. Mitu, “Metal based pharmacologically active agents: synthesis, structural elucidation, DNA interaction, in vitro antimicrobial and in vitro cytotoxic screening of Copper(II) and Zinc(II) complexes derived from amino acid based pyrazolone,” Arabian Journal of Chemistry, vol. 6, no. 2, pp. 235–247, 2013. View at Google Scholar
  37. W. E. Estes, D. P. Gavel, W. E. Hatfield, and D. J. Hodgson, “Magnetic and structural characterization of dibromo- and dichlorobis(thiazole)copper(II),” Inorganic Chemistry, vol. 17, no. 6, pp. 1415–1421, 1978. View at Google Scholar · View at Scopus
  38. J. Garcia, M. C. Molla, J. Borras, and E. Escriva, “Thermal study of mepirizol complexes with Co(II), Ni(II), Cu(II) and Zn(II),” Thermochimica Acta, vol. 106, pp. 155–162, 1986. View at Google Scholar · View at Scopus
  39. S. Funar-Timoftei, L. Crisan, S. Iliescu, G. Bandur, and E. Seclaman, “Conformational analysis of an arylazo phosphate dimer by molecular and quantum mechanics approaches,” Chemical Bulletin of Politehnica Timisoara University, vol. 55, no. 69, pp. 2–10, 2010. View at Google Scholar
  40. N. Raman, A. Kulandaisamy, and K. Jeyasubramanian, “Synthesis, structural characterization, redox and antimicrobial studies of Schiff base copper(II), nickel(II), cobalt(II), manganese(II), zinc(II) and oxovanadium(II) complexes derived from benzil and 2-aminobenzyl alcohol,” Polish Journal of Chemistry, vol. 76, no. 8, pp. 1085–1094, 2002. View at Google Scholar · View at Scopus