Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one Sulfanilamide

Table 2

Zone of growth inhibition exhibited by sulfanilamide Schiff bases and metal complexes at 40 mg/mL (mm).

Ligand and complexes	Staphylococcus aureus	Bacillus pumilus	Proteus vulgaris	Aeromonas hydrophila
2	12.5	7.5	10.3	24.0
1	NI	5.0	8.5	4.0
2a	8.5	NI	NI	8.0
2b	13.3	16.0	NI	15.0
2c	8.0	NI	11.5	21.0
2d	NI	10.3	NI	8.0
1a	NI	NI	NI	8.5
1b	NI	9.0	NI	NI
1c	4.5	6.0	NI	6.0
1d	NI	NI	8.5	15.0
Chloramphenicol	30.0	20.0	42.0	40.0
DMSO	NI	NI	NI	NI

NI = no inhibition.