Oxaliplatin Analogues with Carboxy Derivatives of Boldine with Enhanced Antioxidant Activity

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Compound</td><td align="center">IC<sub>50</sub>  (mM)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">L1</td><td align="center">1.71 ± 0.03</td></tr><tr><td align="left">L5</td><td align="center">3.20 ± 0.10</td></tr><tr><td align="left">L6</td><td align="center">58 ± 8</td></tr><tr><td align="left"><b>1</b></td><td align="center">2.68 ± 0.08</td></tr><tr><td align="left"><b>2</b></td><td align="center">26 ± 9</td></tr><tr><td align="left">Oxaliplatin</td><td align="center">350 ± 70</td></tr><tr><td align="left">Trolox</td><td align="center">0.40 ± 0.01</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Antioxidant activity (IC<sub>50</sub>) in DPPH assay.

Bioinorganic Chemistry and Applications

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Table 1

Table 1: Oxaliplatin Analogues with Carboxy Derivatives of Boldine with Enhanced Antioxidant Activity 