Research Article
Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity
Table 2
Activity (mean ± SD) and selectivity index (SI) of the compounds and benznidazole upon bloodstream trypomastigotes (BT) forms of T. cruzi (Y strain) in vitro (24 h of incubation at 37°C).
| ||||||||||||||||||||||||||||||||||||
SD: standard deviation of multiple experimental measurements. SI: selective index: ratio between LC50/EC50 values. LC50: drug concentration which reduces the viability of mammalian cell by 50%. EC50: drug concentration which reduces the number of the parasites by 50%. Data published in Martins et al., 2012 [14]. |