Novel <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2379999pt" id="M1" height="15.7135pt" version="1.1" viewBox="-0.0657574 -15.4755 25.1166 15.7135" width="25.1166pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g190-71" d="M493 503C489 551 484 614 483 650H43V622C120 616 128 611 128 525V126C128 40 120 34 40 28V0H312V28C221 34 213 40 213 126V307H316C407 307 412 296 424 227H453V420H424C412 355 407 346 316 346H213V584C213 613 216 616 246 616H322C398 616 419 607 436 579C449 559 455 539 464 499L493 503Z"/></g><g transform="matrix(.017,0,0,-0.017,8.75,0)"><path id="g190-102" d="M380 106C343 72 306 56 265 56C195 56 116 112 115 248C235 252 361 262 377 265C396 269 400 277 400 297C400 374 333 449 250 449H249C198 449 144 421 103 376S37 269 37 201C37 88 109 -12 232 -12C263 -12 332 6 395 84L380 106ZM225 412C281 412 315 364 314 312C314 297 308 292 290 292C232 290 176 289 120 289C135 370 180 412 225 412Z"/></g><g transform="matrix(.012,0,0,-0.012,16.105,-7.578)"><path id="g190-74" d="M303 0V28C221 34 213 39 213 125V525C213 610 221 616 303 622V650H38V622C120 616 128 610 128 525V125C128 40 120 34 38 28V0H303Z"/></g><g transform="matrix(.012,0,0,-0.012,20.201,-7.578)"><use xlink:href="#g190-74"/></g></svg> and <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.3069pt" id="M2" height="15.7824pt" version="1.1" viewBox="-0.0657574 -15.4755 29.5089 15.7824" width="29.5089pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g190-68" d="M614 175C564 76 510 21 408 21C256 21 146 149 146 336C146 488 235 629 402 629C510 629 570 586 597 480L626 488C620 541 614 582 606 638C578 643 510 665 429 665C206 665 44 527 44 316C44 157 153 -15 402 -15C474 -15 558 5 586 11C604 45 629 119 643 165L614 175Z"/></g><g transform="matrix(.017,0,0,-0.017,11.67,0)"><path id="g190-112" d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"/></g><g transform="matrix(.012,0,0,-0.012,20.497,-7.578)"><use xlink:href="#g190-74"/></g><g transform="matrix(.012,0,0,-0.012,24.593,-7.578)"><use xlink:href="#g190-74"/></g></svg> Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA

<div>Fluorescence emission spectra of EthBr bound with G4-DNA ([DNA]/[EthBr] = 10 : 1) in the absence (- - - -) and presence (—) of increasing amounts of complexes<b> 1</b> and<b> 2</b> with [complex]/[EthBr] ratios ranging from 0 : 1 to 10 : 1, excited at 453 nm.</div>

Bioinorganic Chemistry and Applications

fig5

Figure 5

Figure 5: Novel <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2379999pt" id="M1" height="15.7135pt" version="1.1" viewBox="-0.0657574 -15.4755 25.1166 15.7135" width="25.1166pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g190-71" d="M493 503C489 551 484 614 483 650H43V622C120 616 128 611 128 525V126C128 40 120 34 40 28V0H312V28C221 34 213 40 213 126V307H316C407 307 412 296 424 227H453V420H424C412 355 407 346 316 346H213V584C213 613 216 616 246 616H322C398 616 419 607 436 579C449 559 455 539 464 499L493 503Z"/></g><g transform="matrix(.017,0,0,-0.017,8.75,0)"><path id="g190-102" d="M380 106C343 72 306 56 265 56C195 56 116 112 115 248C235 252 361 262 377 265C396 269 400 277 400 297C400 374 333 449 250 449H249C198 449 144 421 103 376S37 269 37 201C37 88 109 -12 232 -12C263 -12 332 6 395 84L380 106ZM225 412C281 412 315 364 314 312C314 297 308 292 290 292C232 290 176 289 120 289C135 370 180 412 225 412Z"/></g><g transform="matrix(.012,0,0,-0.012,16.105,-7.578)"><path id="g190-74" d="M303 0V28C221 34 213 39 213 125V525C213 610 221 616 303 622V650H38V622C120 616 128 610 128 525V125C128 40 120 34 38 28V0H303Z"/></g><g transform="matrix(.012,0,0,-0.012,20.201,-7.578)"><use xlink:href="#g190-74"/></g></svg> and <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.3069pt" id="M2" height="15.7824pt" version="1.1" viewBox="-0.0657574 -15.4755 29.5089 15.7824" width="29.5089pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g190-68" d="M614 175C564 76 510 21 408 21C256 21 146 149 146 336C146 488 235 629 402 629C510 629 570 586 597 480L626 488C620 541 614 582 606 638C578 643 510 665 429 665C206 665 44 527 44 316C44 157 153 -15 402 -15C474 -15 558 5 586 11C604 45 629 119 643 165L614 175Z"/></g><g transform="matrix(.017,0,0,-0.017,11.67,0)"><path id="g190-112" d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"/></g><g transform="matrix(.012,0,0,-0.012,20.497,-7.578)"><use xlink:href="#g190-74"/></g><g transform="matrix(.012,0,0,-0.012,24.593,-7.578)"><use xlink:href="#g190-74"/></g></svg> Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA 

Bioinorganic Chemistry and Applications

Novel and Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA

Figure 5