Bioinorganic Chemistry and Applications / 2016 / Article / Tab 1

Research Article

Synthesis, Characterization, Anticancer, and Antioxidant Studies of Ru(III) Complexes of Monobasic Tridentate Schiff Bases

Table 1

In vitro antiproliferative studies of Ru(III)-Schiff base complexes against TK-10, UACC-62, and MCF-7 cell lines.

CompoundsMolecular formulaAnticancer activity IC50 (µM) 48 h
TK-10UACC-62MCF-7

[Ru(DAE)Cl2(H2O)C18H24N3O4RuCl2
Ru(HME)Cl2(H2O)C18H23N2O6RuCl2
Ru(DEE)Cl2(H2O)C17H20N2O4RuCl3
ParthenolideC15H20O3

Standard cytotoxin drug: cell lines were treated with different concentrations of the compounds to achieve 50% inhibition of the culture growth when cultured for 48 h. Value represents mean SD of three independent experimentations.

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