Synthesis of Pyrazolone Derivatives and Their Nanometer Ag(I) Complexes and Physicochemical, DNA Binding, Antitumor, and Theoretical Implementations

Table 4

Cytotoxic activity of tested complexes against human cancer cell lines.

Cell type	IC50 (µg/ml)
	HL^1	Ag(I)-HL^1	HL^2	Ag(I)-HL^2	HL^3	Ag(I)-HL^3	HL^4	Ag(I)-HL^4	Doxorubicin
MCF-7	60.4	60.8	57.7	78.8	14.5	12.81	1.976	16.66	0.168
HepG2	71.3	62.32	63.52	88.5	17.8	11.88	15.86	12.52	0.777
HCT116	36.5	26.8.5	52.6	45.8	20.4	12.8	14.8	8.42	0.9255