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Bioinorganic Chemistry and Applications
Volume 2018, Article ID 8459638, 10 pages
https://doi.org/10.1155/2018/8459638
Research Article

Hydrothermal Synthesis, Structural Characterization, and Interaction Mechanism with DNA of Copper(II) Complex Containing 2,2′-Bipyridine

School of Material Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China

Correspondence should be addressed to Guo-Qing Zhong; moc.361@613qgz

Received 28 February 2018; Accepted 8 April 2018; Published 22 May 2018

Academic Editor: Concepción López

Copyright © 2018 Ting Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A Cu(II) complex [Cu(bipy)(H2O)2(SO4)]n (bipy = 2,2′-bipyridine) was synthesized by hydrothermal method and characterized structurally by elemental analyses, single crystal X-ray diffraction, infrared spectra, and thermogravimetry and differential scanning calorimetry. The Cu(II) was hexacoordinated by two N atoms from bipy, two O atoms from different sulfate radical anions, and two O atoms from two water molecules, forming a slightly distorted octahedral geometry, and bridged by sulfato groups into polymeric chains. Under the condition of physiological pH, the interaction mechanism between the complex and hsDNA was explored with acridine orange as a fluorescence probe by spectroscopic methods. The binding modes between the complex and hsDNA were the electrostatic and embedded modes.