Bioinorganic Chemistry and Applications / 2020 / Article / Fig 4

Research Article

Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of Angelica gigas Nakai

Figure 4

The inhibitory effect of water extracts of different processed AGN on the human Kv1.3 channel currents. (a) Current traces were evoked by 1 s depolarization to +60 mV from a holding potential of −80 mV under the control condition and exposure to water extracts of different processed AGN. (b) Plot of normalized currents measured at their peak under the control condition and exposure to various concentrations of WES. Each control current was normalized to 1 (n = 4). Values in the same column are significantly different by Duncan’s multiple range test ().
(a)
(b)

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