Synthesis and Characterization of Green Zinc Oxide Nanoparticles with Antiproliferative Effects through Apoptosis Induction and MicroRNA Modulation in Breast Cancer Cells
Table 4
The t-test was performed for the comparison of microRNA expression between control and treatment groups in the MCF7 and HFF cell lines.
Variable
miR-155-5p expression (fold change)
value
HFF
Control
1.00 ± 0.24
0.015
Treatment
2.15 ± 0.32
MCF7
Control
1.00 ± 0.22
0.016
Treatment
0.35 ± 0.32
Variable
miR-223-3p expression (fold change)
value
HFF
Control
1.00 ± 0.19
0.011
Treatment
2.57 ± 0.32
MCF7
Control
1.00 ± 0.25
0.008
Treatment
0.12 ± 0.09
Variable
miR-203-3p expression (fold change)
value
HFF
Control
1.00 ± 0.24
0.025
Treatment
0.40 ± 0.13
MCF7
Control
1.00 ± 0.13
0.008
Treatment
0.14 ± 0.12
Abbreviations: MCF7: Michigan Cancer Foundation-7, HFF: human foreskin fibroblasts, and miR: microRNA.