Research Article

Synthesis and Characterization of Green Zinc Oxide Nanoparticles with Antiproliferative Effects through Apoptosis Induction and MicroRNA Modulation in Breast Cancer Cells

Table 4

The t-test was performed for the comparison of microRNA expression between control and treatment groups in the MCF7 and HFF cell lines.

VariablemiR-155-5p expression (fold change) value

HFFControl1.00 ± 0.240.015
Treatment2.15 ± 0.32

MCF7Control1.00 ± 0.220.016
Treatment0.35 ± 0.32

VariablemiR-223-3p expression (fold change) value

HFFControl1.00 ± 0.190.011
Treatment2.57 ± 0.32

MCF7Control1.00 ± 0.250.008
Treatment0.12 ± 0.09

VariablemiR-203-3p expression (fold change) value

HFFControl1.00 ± 0.240.025
Treatment0.40 ± 0.13

MCF7Control1.00 ± 0.130.008
Treatment0.14 ± 0.12

Abbreviations: MCF7: Michigan Cancer Foundation-7, HFF: human foreskin fibroblasts, and miR: microRNA.