Research Article

Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode

Figure 4

5-FOA binding mode of ScDHOase. Arg18, Asn43, His262, Thr105, Thr106, and Lys230 of ScDHOase were involved in the 5-FOA binding.