Novel Synthesis of Titanium Oxide Nanoparticles: Biological Activity and Acute Toxicity Study

Figure 5

Light micrographs in kidney of (a) control group demonstrating normal histological architecture. Kidney of rats which received low-dose TiO₂ NPs (b) demonstrating most of convoluted tubules were apparently normal (yellow star). Few tubules have cytoplasmic vacuolations in their lining cells (red star). The kidney of rats which received high-dose TiO₂ NPs (c) demonstrating swelling and dilatation of Bowman’s capsule (black arrows), glomerular congestion or inflamed glomeruli (red arrows), nuclear alterations (thick black arrows), and necrotic renal tubules (yellow star). H & E staining 400x magnification.

(a)

(b)

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