Novel Synthesis of Titanium Oxide Nanoparticles: Biological Activity and Acute Toxicity Study

Table 5

Biochemical tests in blood serum of different rat groups.

Dose/test	Control group	Group 2 (received 10 mg/kg)	Group 3 (received 1000 mg/kg)
Urea (mg/dl)	17.30 ± 0.95	6.63 ± 1.47	18.40 ± 0.17
Creatinine (mg/dl)	0.80 ± 0.63	0.52 ± 0.47	0.98 ± 0.94
Glucose (mg/dl)	80.10 ± 0.11	63.78 ± 0.09	73.62 ± 0.04
Cholesterol (md/dl)	50.70 ± 0.03^a	15.95 ± 0.02^a	69.94 ± 0.06^a
Total protein (mg/dl)	5.90 ± 0.41	3.24 ± 0.08	4.61 ± 0.23
Albumin (g/dl)	4.20 ± 0.90	2.91 ± 1.73	3.52 ± 1.46
Uric acid (g/dl)	2.80 ± 0.37^b	2.09 ± 0.51^b	5.26 ± 0.48^b
Bilirubin (mg/dl)	0.50 ± 0.01	0.57 ± 0.01	0.59 ± 0.03
Alk phos (U/L)	131.00 ± 1.49^C	60.53 ± 1.73^C	274.52 ± 1.97^C
GGT (U/L)	70.00 ± 0.77^d	68.71 ± 2.80^d	226.97 ± 1.32^d
ALT (U/L)	11.00 ± 0.21^e	24.64 ± 0.13^e	100.69 ± 0.61^e
AST (U/L)	27.00 ± 0.92^f	140.26 ± 0.45^f	431.84 ± 0.28^f

All values are expressed as mean ± SD. Different letters of the same column are significantly different at .