Synthesis, Structure, and Biologic Activity of Some Copper, Nickel, Cobalt, and Zinc Complexes with 2-Formylpyridine N⁴-Allylthiosemicarbazone

Table 7

IC₅₀ values of the synthesized substances toward ABTS^•+ radical cation.

Compound	IC50, μM
HL	14.2 ± 1.8
HL^a	19.1 ± 0.9
HL^b	20.6 ± 1.1
[Zn(H2O) (L)Cl] (1)	24.7 ± 1.3
[Cu(L)Cl] (2)	>100
[Cu(L)Br] (3)	43.0 ± 2.1
[Cu2L2(CH3COO)2]·4H2O (4)	40.3 ± 1.8
[Ni(HL)2]Cl2·H2O (5)	8.6 ± 0.1
[Co(L)2]Cl (6)	>100
Trolox	33.0 ± 0.7