Deferiprone−Resveratrol Hybrid, an Iron-Chelating Compound, Acts as an Antimalarial and Hepatoprotective Agent in Plasmodium berghei-Infected Mice

Figure 5

Heme iron concentrations of the plasma (a) and liver (b) of normal mice and PbANKA-infected mice treated with 60% DMSO, DFP-RVT (50 mg/kg BW), DFP (50 mg/kg BW), and PYR (2 mg/kg BW) for 8 consecutive days. Data are expressed as mean ± SEM values (n = 3 each). Accordingly, when compared with the normal group; and when compared with the PbANKA-infected group treated with DMSO.

(a)

(b)