Research Article
Deferiprone−Resveratrol Hybrid, an Iron-Chelating Compound, Acts as an Antimalarial and Hepatoprotective Agent in Plasmodium berghei-Infected Mice
Table 3
Levels of AST, ALT, and ALP activities in the plasma of normal mice and PbANKA-infected mice treated with 60% DMSO, DFP (50 mg/kg), DFP-RVT (50 mg/kg), and PYR (2 mg/kg) (n = 3 each) for 8 consecutive days. Data are expressed as mean ± SEM values. Accordingly, when compared with the normal group; and when compared with mice in the PbANKA-infected group that had been treated with DMSO.
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ALP = alkaline phosphatase, ALT = alanine aminotransferase, AST = aspartate aminotransferase, DFP = deferiprone, DFP-RVT = deferiproneresveratrol, DI = deionized water, DMSO = dimethylsulfoxide, PbANKA = Plasmodium berghei ANKA strain, and PYR = pyrimethamine. |