A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η¹-C₂H₄OMe)(DMSO)(phen)]⁺ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells

Figure 7

Summary of metabolic analysis conducted using MetaboAnalyst considering the 6 hours after treatment of Pt-EtOMeSOphen vs. controls. (a) Glycine, serine, and threonine metabolism. (b) Pyruvate metabolism. (c) Glutathione metabolism. Colors, varying from yellow to red, mean that the metabolites are in the data with different levels of significance (yellow: -value <0.1; light orange: -value <0.05; orange: -value <0.01; and red: -value <0.001). Circle size, varying from small to big, means the impact of metabolites in data on the pathways alteration (small circle: low impact and large circle: high impact).