[Retracted] Development of Microneedle Patch Loaded with Bacopa monnieri Solid Lipid Nanoparticles for the Effective Management of Parkinson’s Disease

Table 1

Dependent and independent variables are taken in the optimization of formulations.

Factors	Levels, actual (coded)
	−1 (Low)	0 (Medium)	+1 (High)
Independent variables
A = drug: GMS ratio (W:W)	1:1	1:2	1:3
B = sonication time (min)	5	7.5	10
Dependent variables
R1 = particle size (nm; R1)
R2 = entrapment efficiency (%; R2)
R3 = polydispersity index (R3)