[Retracted] Development of Microneedle Patch Loaded with Bacopa monnieri Solid Lipid Nanoparticles for the Effective Management of Parkinson’s Disease

Table 2

DOE batches with results of particle size (nm), entrapment efficiency (%), and polydispersity index.

Formulation code	Factor 1 A: drug: lipid (w:w)	Factor 2 B: sonication time (min)	Response 1, particle size (nm)	Response 2, EE (%)	Response 3, PDI
F1	−1	−1	168	78.26	0.445
F2	0	−1	169	78.5	0.38
F3	1	−1	168	78.4	0.42
F4	−1	0	167	73.5	0.43
F5	0	0	146	81.4	0.37
F6	1	0	161	79.3	0.41
F7	−1	1	135	87.9	0.34
F8	0	1	139	85.3	0.36
F9	1	1	128	89	0.28