New Organotin (IV) Compounds Derived from Dehydroacetic Acid and Thiosemicarbazides: Synthesis, Rational Design, Cytotoxic Evaluation, and Molecular Docking Simulation

<div>Representation of the interactions between the A B-DNA dodecamer and diorganotin (IV) derivatives <b>3c-e</b> and Cisplatin. The interactions and DNA residues are shown (red) in the 3D and 2D models. Conventional hydrogen bonds (dark green dotted lines), carbon-hydrogen bonds (light green), <i>π</i>-sigma (purple), <i>π</i>-<i>π</i> T-shaped (Fuchsia), <i>π</i>-alkyl (pink), and <i>π</i>-anions (orange) are also shown in 3D and 2D.</div>

Bioinorganic Chemistry and Applications

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Figure 15

Figure 15: New Organotin (IV) Compounds Derived from Dehydroacetic Acid and Thiosemicarbazides: Synthesis, Rational Design, Cytotoxic Evaluation, and Molecular Docking Simulation 

Figure 15 | New Organotin (IV) Compounds Derived from Dehydroacetic Acid and Thiosemicarbazides: Synthesis, Rational Design, Cytotoxic Evaluation, and Molecular Docking Simulation 