950934.fig.002
Figure 2: Multiparametric flow cytometry analysis of representative MDS bone marrow. Multiparametric flow cytometry analysis of a representative MDS case using the same analytical scheme and color coding as described in Figure 1. G-M progenitors (green) contain an accumulation of cells in G2 with diminished mitosis (M) compared to G-M progenitors in the control marrow (Figure 1). In this case erythroid precursors (red) and CD34+ stem cells (blue) exhibit relatively normal cell cycle parameters (DNA content, mitotic cells) versus the control sample (Figure 1).