Research Article

Infectomic Analysis of Gene Expression Profiles of Human Brain Microvascular Endothelial Cells Infected with Cryptococcus neoformans

Figure 5

The upregulated and downregulated gene profiles of HBMEC during C. neoformans infection. (a) Upregulated genes (left chart): cytochrome P450 gene was continuously upregulated during the course of infection. Genes that have correlation at least 0.95 to the expression profile of cytochrome P450 are grouped and defined as upregulated genes. (b) Downregulated genes (right chart): TNNI3 gene was continuously downregulated during the course of infection. Genes that have correlation at least 0.95 to the expression profile of TNNI3 are grouped and defined as downregulated genes.
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(a)
375620.fig.005b
(b)