The Leishmania HSP20 Is Antigenic during Natural Infections, but, as DNA Vaccine, It does not Protect BALB/c Mice against Experimental L. amazonensis Infection

Figure 3

Antigenicity of Leishmania HSP20 in experimentally infected hamsters. (a) Reactivity against total L. infantum proteins (LAg) or L. amazonensis recombinant HSP20 (rHSP20) of sera from L. infantum infected hamsters is indicated as the mean optical density read at 450 nm (OD₄₅₀). Horizontal lines represent the cut-off values for the assay, which were 0.286 for LAg and 0.067 for rHSP20. (b) and (c) Time course of the humoral response against total antigens (LAg) or rHSP20 elicited in two experimentally infected hamsters.

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