Expression and Hydroxylamine Cleavage of Thymosin Alpha 1 Concatemer
Figure 8
Tα1 (cleaved and synthesized) induced a decrease in the
mitochondrial activity in the SPC-A 1 and HepG2 cells. (a) The SPC-A1 cells were treated with the indicated concentrations
of Tα1 for 24 hours, 48 hours, and 72 hours. MTT assay was used to measure the mitochondrial
activity. Significant decreases in the mitochondrial activity, as compared to
the control, occurred after 48 hours of Tα1 treatment. (b) The HepG2 cells were treated with the indicated concentrations
of Tα1 for 24 hours, 48 hours, and 72 hours. MTT assay was used to measure the mitochondrial
activity. Significant decreases in the mitochondrial activity, as compared to the
control, occurred after 48 hours of Tα1 treatment. All the results are expressed as the mean ±SEM of data
obtained in 3 independent experiments (,
relative to control).
