Table of Contents Author Guidelines Submit a Manuscript
Journal of Biomedicine and Biotechnology
Volume 2009, Article ID 125412, 5 pages
http://dx.doi.org/10.1155/2009/125412
Research Article

Nuclear Phosphatidylcholine and Sphingomyelin Metabolism of Thyroid Cells Changes during Stratospheric Balloon Flight

1Department of Clinical and Experimental Medicine, Physiopathology Section, School of Medicine University of Perugia, 06100 Perugia, Italy
2Polispecialistica Bios, 88900 Crotone, Italy
3Department of Experimental and Clinical Pathology and Medicine, University of Udine, 33100 Udine, Italy

Received 2 July 2009; Accepted 16 September 2009

Academic Editor: Yusuf Hannun

Copyright © 2009 Elisabetta Albi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. A. Francis, E. Fayard, F. Picard, and J. Auwerx, “Nuclear receptors and the control of metabolism,” Annual Review of Physiology, vol. 65, pp. 261–311, 2003. View at Publisher · View at Google Scholar
  2. R. Bhandari and P. K. Sharma, “Effect of UV-B and high visual radiation on photosynthesis in freshwater (Nostoc spongiaeforme) and marine (Phormidium corium) cyanobacteria,” Indian Journal of Biochemistry & Biophysics, vol. 44, pp. 231–239, 2007. View at Google Scholar
  3. A. Anwar, M. Gu, S. Brady et al., “Photoprotective effects of bucillamine against UV-induced damage in an SKH-1 hairless mouse model,” Photochemistry and Photobiology, vol. 84, no. 2, pp. 477–483, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. C. S. Sander, F. Hamm, P. Elsner, and J. J. Thiele, “Oxidative stress in malignant melanoma and non-melanoma skin cancer,” British Journal of Dermatology, vol. 148, no. 5, pp. 913–922, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Alam, Moinuddin, and S. Jabeen, “Immunogenicity of mitochondrial DNA modified by hydroxyl radical,” Cellular Immunology, vol. 247, no. 1, pp. 12–17, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. F. R. de Gruijl, “Skin cancer and solar UV radiation,” European Journal of Cancer, vol. 35, no. 14, pp. 2003–2009, 1999. View at Google Scholar
  7. K. Rass and J. Reichrath, “UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer,” Advances in Experimental Medicine and Biology, vol. 624, pp. 162–178, 2008. View at Google Scholar · View at Scopus
  8. M. Oren and J. Bartek, “The sunny side of p53,” Cell, vol. 128, no. 5, pp. 826–828, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Norval, P. McLoone, A. Lesiak, and J. Narbutt, “The effect of chronic ultraviolet radiation on the human immune system,” Photochemistry and Photobiology, vol. 84, no. 1, pp. 19–28, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. E. Albi, S. Cataldi, G. Rossi et al., “The nuclear ceramide/diacylglycerol balance depends on the physiological state of thyroid cells and changes during UV-C radiation-induced apoptosis,” Archives of Biochemistry and Biophysics, vol. 478, no. 1, pp. 52–58, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. E. Albi and M. P. Viola Magni, “The role of intranuclear lipids,” Biology of the Cell, vol. 96, no. 8, pp. 657–667, 2004. View at Google Scholar
  12. A. M. Rizzo, F. Rossi, S. Zava et al., “Antioxidant metabolism in Xenopus laevis embryos is affected by stratospheric balloon flight,” Cell Biology International, vol. 31, no. 7, pp. 716–723, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Zanini, C. Ongaro, and L. Tommasino, “Neutron spectrometry at various altitudes. Atmosphere by passive detector technique,” Il Nuovo Cimento, vol. 24, pp. 691–767, 2001. View at Google Scholar
  14. E. Del Terra, A. Francesconi, D. Donnini, F. Curcio, and F. S. Ambesi-Impiombato, “Thyrotropin effects on ultraviolet radiation-dependent apoptosis in FRTL-5 cells,” Thyroid, vol. 13, no. 8, pp. 747–753, 2003. View at Google Scholar · View at Scopus
  15. E. Albi, R. Lazzarini, and M. Viola Magni, “Phosphatidylcholine/sphingomyelin metabolism crosstalk inside the nucleus,” Biochemical Journal, vol. 410, no. 2, pp. 381–389, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. M. D. Temple, G. G. Perrone, and I. W. Dawes, “Complex cellular responses to reactive oxygen species,” Trends in Cell Biology, vol. 15, no. 6, pp. 319–326, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. G. W. Thorpe, C. S. Fong, N. Alic, V. J. Higgins, and I. W. Dawes, “Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 17, pp. 6564–6569, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Satoh, X. Li, H. Yokota et al., “Regulation by sphingolipids of the fate of FRTL-5 cells,” Journal of Biochemistry, vol. 145, no. 1, pp. 31–36, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. F. S. Ambesi-Impiombato, L. A. M. Parks, and H. G. Coon, “Culture of hormone-dependent functional epithelial cells from rat thyroids,” Proceedings of the National Academy of Sciences of the United States of America, vol. 77, pp. 3455–3459, 1980. View at Google Scholar · View at Scopus