Characterization of a Novel Polymorphism in PPARG Regulatory Region Associated with Type 2 Diabetes and Diabetic Retinopathy in Italy

Table 4

Genotypes and -2819G frequency in diabetic women with and without proliferative retinopathy (statistical significant values are in bold).

(a)

	Diabetic female with background retinopathy	Diabetic female with proliferative retinopathy
n	55	57
A-2819G
A/A	43 (78%)	34 (60%)
A/G	11 (22%)	21 (36.7%)
G/G	0 (0%)	2 (3.3%)

(b)

SNP	Risk allele	Frequency of risk allele		Risk allele odds ratio (95% C.I.)	P value; statistical power (%)
A-2819G	G	Diabetic female with background retinopathy	Diabetic female with proliferative retinopathy	Background/proliferative	Background/proliferative
		0.11	0.22	2.30 (1.09-4.83)	𝟎.𝟎𝟐;𝟔𝟔.𝟑%