Effects of FR-91 on Immune Cells from Healthy Individuals and from Patients with Non-Hodgkin Lymphoma
Figure 1
Flow cytometric analysis of CD3 and CD4 expressions in a normal individual and in a patient with NHL. Blue histograms represent untreated lymphocytes, green histograms represent lymphocytes treated with 10 g/mL of FR-91, and red histograms represent lymphocytes treated with 25 g/mL of FR-91. Flow cytometric analysis in (a) shows a reduction in CD3 antigen expression after exposure to 25 g/mL of FR-91, while an increase in both green and red histograms can be observed in the NHL patients (b). A similar pattern of CD4 expression can be observed both in the normal patient as well as in the NHL patient, being the expression of CD4 higher after treatment with 10 g/mL of FR-91 (d).
