Table of Contents Author Guidelines Submit a Manuscript
Journal of Biomedicine and Biotechnology
Volume 2009, Article ID 275287, 7 pages
http://dx.doi.org/10.1155/2009/275287
Review Article

Rational Design of Improved Pharmabiotics

1Alimentary Pharmabiotic Centre, University College Cork, Ireland
2Department of Biological Sciences, Cork Institute of Technology, Rossa Avenue, Bishopstown, Cork, Ireland

Received 3 April 2009; Revised 18 June 2009; Accepted 22 June 2009

Academic Editor: Don Mark Estes

Copyright © 2009 Roy D. Sleator and Colin Hill. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [17 citations]

The following is the list of published articles that have cited the current article.

  • Piret Koll, Reet Maendar, Imbi Smidt, Pirje Huett, Kai Truusalu, Raik-Hiio Mikelsaar, Jelena Shchepetova, Kasper Krogh-Andersen, Harold Marcotte, Lennart Hammarstrom, and Marika Mikelsaar, “Screening and Evaluation of Human Intestinal Lactobacilli for the Development of Novel Gastrointestinal Probiotics,” Current Microbiology, vol. 61, no. 6, pp. 560–566, 2010. View at Publisher · View at Google Scholar
  • M. Blaha, J. Pit'ha, V. Blaha, M. Lanska, J. Maly, S. Filip, and H. Langrova, “Extracorporeal Immunoglobulin Elimination for the Treatment of Severe Myasthenia Gravis,” Journal of Biomedicine and Biotechnology, vol. 2010, pp. 1–6, 2010. View at Publisher · View at Google Scholar
  • Roy D. Sleator, “Probiotic therapy - recruiting old friends to fight new foes,” Gut Pathogens, vol. 2, 2010. View at Publisher · View at Google Scholar
  • M. Bláha, H. Vlcková, L. Nováková, D. Solichová, P. Solich, M. Lánská, J. Malý, and V. Bláha, “Use of Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry to Demonstrate Decreased Serum Statin Levels after Extracorporeal LDL-Cholesterol Elimination,” Journal of Biomedicine and Biotechnology, vol. 2011, pp. 1–9, 2011. View at Publisher · View at Google Scholar
  • Borja Sánchez, Lorena Ruiz, Miguel Gueimonde, Patricia Ruas-Madiedo, and Abelardo Margolles, “Toward improving technological and functional properties of probiotics in foods,” Trends in Food Science & Technology, vol. 26, no. 1, pp. 56–63, 2012. View at Publisher · View at Google Scholar
  • Audrey Feeney, and Roy D Sleator, “The human gut microbiome: the ghost in the machine,” Future Microbiology, vol. 7, no. 11, pp. 1235–1237, 2012. View at Publisher · View at Google Scholar
  • Alisson Santana da Silva, Edson Renato Honjoya, Osney Massami Inay, Marcela de Rezende Costa, Cinthia Hoch Batista de Souza, Elsa Helena Walter de Santana, Helio Hiroshi Suguimoto, and Lina Casale Aragon-Alegro, “Viability of Lactobacillus casei in chocolate flan and its survival to simulated gastrointestinal conditions,” Semina-Ciencias Agrarias, vol. 33, pp. 3163–3170, 2012. View at Publisher · View at Google Scholar
  • Christopher Johnston, Pierre E. Douarre, Tewfik Soulimane, Daniel Pletzer, Helge Weingart, John MacSharry, Aidan Coffey, Roy D. Sleator, and Jim O'Mahony, “ Codon optimisation to improve expression of a Mycobacterium avium ssp. paratuberculosis- specific membrane-associated antigen by Lactobacillus salivarius ,” Pathogens and Disease, vol. 68, no. 1, pp. 27–38, 2013. View at Publisher · View at Google Scholar
  • Borja Sánchez, Lorena Ruiz, Miguel Gueimonde, Patricia Ruas-Madiedo, and Abelardo Margolles, “Adaptation of bifidobacteria to the gastrointestinal tract and functional consequences,” Pharmacological Research, vol. 69, no. 1, pp. 127–136, 2013. View at Publisher · View at Google Scholar
  • Roland F. Hoffmann, Susan McLernon, Audrey Feeney, Colin Hill, and Roy D. Sleator, “A single point mutation in the listerial betL σA-dependent promoter leads to improved osmo- and chill-tolerance and a morphological shift at elevated osmolarity,” Bioengineered, vol. 4, no. 6, pp. 18–17, 2013. View at Publisher · View at Google Scholar
  • Eamonn P Culligan, Roy D Sleator, Julian R Marchesi, and Colin Hill, “Metagenomics and novel gene discovery: Promise and potential for novel therapeutics,” Virulence, vol. 5, no. 3, pp. 399–412, 2014. View at Publisher · View at Google Scholar
  • Zhongke Sun, Christina Westermann, Jing Yuan, and Christian U Riedel, “Experimental determination and characterization of the gap promoter of Bifidobacterium bifidum S17,” Bioengineered, vol. 5, no. 6, 2014. View at Publisher · View at Google Scholar
  • Roy D. Sleator, “Under the microscope: From Pathogens to Probiotics and Back,” Bioengineered, pp. 00–00, 2015. View at Publisher · View at Google Scholar
  • Roy Sleator, “Engineering of Probiotics for Technological and Physiological Functionalities,” Advances in Probiotic Technology, pp. 168–176, 2015. View at Publisher · View at Google Scholar
  • Roy D Sleator, “Designer probiotics: Development and applications in gastrointestinal health.,” World journal of gastrointestinal pathophysiology, vol. 6, no. 3, pp. 73–8, 2015. View at Publisher · View at Google Scholar
  • Lorena Ruiz, Miguel Gueimonde, Patricia Ruas-Madiedo, Abelardo Margolles, and Borja Sánchez, “Improving Probiotics for Functional Foods,” Advances in Food Biotechnology, pp. 351–368, 2015. View at Publisher · View at Google Scholar
  • Babasola Sola-Oladokun, Eamonn P. Culligan, and Roy D. Sleator, “Engineered Probiotics: Applications and Biological Containment,” Annual Review of Food Science and Technology, vol. 8, no. 1, pp. 353–370, 2017. View at Publisher · View at Google Scholar