Review Article

Rational Design of Improved Pharmabiotics

Figure 4

Improved clinical efficacy. Probiotic dosing of BALB/c mice with B. breve (black) significantly (**, ) reduces the level of subsequent L. monocytogenes infection when compared to the wild-type B. breve strain. Bacterial growth was followed in (a) the liver and (b) the spleen 3 days postinfection, adapted from Watson et al. [20].
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(a)
275287.fig.004b
(b)