The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent

Figure 1

Epistasis interaction between mag1∆ and pol3-t (a); and rad50 ∆ and pol3-t (b). All strains were isogenic to RSY6. Single colonies of each strain were pregrown at 25^∘C for 24 hours and exposed to MMS for 4 hours at 30^∘C as reported in the materials and methods. Data are reported as the mean of six or more independent experiments ± standard deviation.

(a)

(b)