Research Article

The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent

Table 5

Effect of pol3-t on UV-induced intrachromosomal recombination in RAD + and rad50 strains.

StrainUV% survivalIntrachromosomal Recombination
(J/m2)( )

RSY6 (POL3 RAD50)01006.2 1.4
577 158.4 1.9
1062 2310 2.9
10041 8.720 6.2*
50027 8.328 5.6**

AGY30 (pol3-t)010014 1.7
569 1417 3.4
1069 1113 2.0
10057 1325 6*
50039 3.522 3*

YR50-1 (rad50Δ)01001.2 0.6
568 111.7 0.6
1048 281.5 0.8
10039 192.5 1.5
20035 171.3 0.7
50016 92.6 0.2**

AGY34 (rad50Δpol3-t)01001.9 0.8
570 102.0 0.7
1071 222.3 0.9
10062 174.3 1.5*
20034 94.5 0.7**
50026 124.8 1.1**

See legend to Table 4.