BioMed Research International / 2009 / Article / Tab 1

Research Article

Duchenne and Becker Muscular Dystrophy: Contribution of a Molecular and Immunohistochemical Analysis in Diagnosis in Morocco

Table 1

Clinical data, and genetic and immunohistochemical results for our patients.

Age (years)Age at onset (years)ConsanguinityImmunochemistry Deleted exonsOther criterion
Dys-C α-SG γ-SG

1135No++++++50, 51, and 52Elevated SCK activity at the mother
293No++++++45, 47, 48, 50, 51, and 52Maternal uncle died
3124No++++++51 and 52Elevated SCK activity at the mother
4165No++++++Elder brother with the same symptoms
5113Yes++++++45 and 48
6133No++++++45
7125No+/−++++++12, 13, 17, 19, 43, 44, 45, 47, and 48
8135Yes+/−++++++3, 4, 6, and 8
9132Yes+++48521del T in γ-SG gene not found
101911Yes+++++Pm521del T in γ-SG gene not found

+++: normal; +: reduced; +/−: irregular; − : absent
: patient number; SG: sarcoglycan; Dys: dystrophin; SCK: serum creatine kinase.