Inhibitory Effect of Flavonoids on the Efflux of -Acetyl 5-Aminosalicylic Acid Intracellularly Formed in Caco-2 Cells
Figure 4
The effect of flavonols and transpoter inhibitors on the cellular accumulation of N-acetyl 5-aminosalicylic acid in Caco-2 cells. Caco-2 cells grown in tissue culture dishes were incubated with 200 M 5-ASA for 2 hours in the presence of flavonols and transporter inhibitors at the concentration of 100 M. Cellular accumulation percent : (cells/cells plus medium) 100. Each bar represents the mean SD of four to five experiments. Significant difference from control *, **.