BioMed Research International / 2009 / Article / Tab 2

Research Article

High Specificity of Quantitative Methylation-Specific PCR Analysis for MGMT Promoter Hypermethylation Detection in Gliomas

Table 2

MGMT promoter methylation status in primary tumour and recurrences by quantitative methylation-specific PCR (QMSP) and Methylation-Specific PCR (MSP).

PatientHystological* typeMonths§Sample#QMSPQMSPMSP




*GB: Glioblastoma. §number of months from first surgery. #FFPE: Formalin fixed paraffin-embedded sample; SF: Snap-frozen pecimen. IQR: Interquartile range; pos: Methylation levels for QMSP exceed the cutoff point of 0.35, a band is seen in gel electrophoresis for MSP; neg: Methylation levels for QMSP are below the cutoff point of 0.35, no band is seen in gel electrophoresis for MSP.

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