BioMed Research International / 2009 / Article / Fig 8

Research Article

Effects of Chronic Mild Stress on the Development of Atherosclerosis and Expression of Toll-Like Receptor 4 Signaling Pathway in Adolescent Apolipoprotein E Knockout Mice

Figure 8

MCP-1, sICAM-1, and TNF-a levels in the serum of apoE-/- mice were analyzed by ELISA. IL-1 (a), TNF-a (b), sICAM-1 (c), and MCP-1 (d) levels markedly increased in the serum of apoE mice following different weeks of CMS compared with the corresponding control group ( per group). These cytokines were measured by ELISA according to the manufacturer’s instructions. Data are mean   SEM. *P , **P , ***P versus respective control value.

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