Integrating Diverse Information to Gain More Insight into Microarray Analysis
Table 3
The important set of genes based on topological structure of interaction network. Selecting the nodes that satisfy condition 2 (the articulation nodes among the hub nodes of the network) and condition 3 (the hub nodes of the minimum spanning tree). The inverse of fold changes for down regulated genes is shown. Thus the table includes the genes that are not considered in the experiment or neither up-or downregulated.
Gene
Regulation
Fold change
CPNE1
Up
2.63
CTSB
Up
2.78
CTSD
Up
2.00
MAD1L1
Up
3.45
MEF2C
Up
2.21
PCM1
Up
2.01
PRKAR2B
Up
2.80
PSMD7
Up
2.01
PTPN1
Up
2.06
RBL2
Up
2.62
RGS20
Up
2.20
SOD2
Up
2.10
ADSL
Down
2.23
ATM
Down
2.09
BID
Down
2.09
CASP1
Down
3.07
CBLB
Down
2.32
CCNB2
Down
2.32
CDC7
Down
2.17
CHEK1
Down
2.06
CTTN
Down
2.63
DDX17
Down
2.13
DGCR14
Down
2.04
ETS1
Down
2.50
FOS
Down
2.94
GLUL
Down
5.13
GNAQ
Down
2.39
ID2
Down
2.86
MACF1
Down
2.05
MRE11A
Down
2.61
MYLK
Down
4.25
NEDD4
Down
2.01
PAFAH1B2
Down
2.57
PPFIA1
Down
2.41
PRKAB2
Down
2.56
PRSS23
Down
2.47
RAB27A
Down
2.74
RAB8B
Down
2.27
RPL31
Down
2.08
RRM2
Down
2.32
SMARCB1
Down
2.14
SNCA
Down
5.24
TGFB2
Down
2.06
THBS1
Down
3.70
TNFRSF1A
Down
2.13
TPM1
Down
4.62
XRCC6
Down
2.08
DDX19B
Down
2.09
*GRINL1B
—
—
*HIST2H3PS2
—
—
*NA
—
—
*RET
—
—
*RPL35A
—
—
**SMC2
—
—
**SMC4
—
—
**TPI1
—
—
**TUBA4A
—
—
hese genes are neither up-or downregulated, nor considered in the experiment.hese genes are from interaction network that satisfy conditions 2 and 3.
