Molecular Cloning, Characterization, and Expression Analysis of the CXCR4 Gene from Turbot: Scophthalmus maximus

Figure 2

Neighbor-Joining tree of the amino-acid sequences of CXCR4. Numbers at tree nodes refer to percent bootstrap values after 1000 replicates; the scale bar refers to a phylogenetic distance of 0.1 amino acid substitutions per site. CXCR6 of Rattus norvegicus was used as outgroup. Turbot CXCR4 is underlined. The GenBank accession numbers of the sequences are as follows, CXCR4: D. rerio, AAH50172; C. carpio, BAA32797; O. latipes, ABC41565; A. ruthenus, CAB60252; H. sapiens, CAA12166; Hylobates hoolock, AAF89348; Canis familiaris, ABA28309; Bos Taurus, AAI05218; G. gallus, AAG09054; M. musculus, BAA19187; Xenopus laevis, AAI10722. CXCR: Oncorhynchus mykiss, CAA04493; Oryctolagus cuniculus, ABX55954; Felis catus, CAA08839; R. norvegicus, AAB50408. CXCR6: R. norvegicus, AAZ66333.