Hypercholesterolaemic Serum Increases the Permeability of Endothelial Cells through Zonula Occludens-1 with Phosphatidylinositol 3-Kinase Signaling Pathway
Figure 3
Hypercholesterolemic serum could significantly increase the permeability of endothelial cells, which was detected by albumin permeability test with transwell. And the permeability of endothelial cells increased with the concentration of hypercholesterolemic serum. a: serum free medium; b: normal rabbit serum; c: low concentration of hypercholesterolemic serum (0.04 mMol/L); d: high concentration of hypercholesterolemic serum (0.32 mMol/L); e: c plus 100 nMol/L wortmannin; f: d plus 100 nMol/L. * represents compared with serum-free medium control; # represents compared with previous group.
