Research Article

The Roles of Platelet GPIIb/IIIa and αvβ3 Integrins during HeLa Cells Adhesion, Migration, and Invasion to Monolayer Endothelium under Static and Dynamic Shear Flow

Figure 7

Effect of platelets, thrombin, eptifibatide, and RGDWE peptides on adhesion of HeLa cells to HUVECs monolayer under static (0 dyn/cm2) and low shear stress conditions (1.84 dyn/cm2, 1 hour). (b) and (c) are the representative images of HeLa cells adhesion (labelled into green) and the statistical data of adhered HeLa cell numbers in various conditions, respectively. The numbers of adhered HeLa cells were quantified by cell counting from more than ten micrographic fields using magnification of 10×. * flow versus static; ** (Flow+Pl+Ep) versus (Flow+Pl+Th); # (Flow+RGDWE); ## (Flow+Pl) versus Flow.
829243.fig.007a
(a)
829243.fig.007b
(b)