A Novel Flow-Perfusion Bioreactor Supports 3D Dynamic Cell Culture
Figure 1
(a) With increased medium fluid flow across the external surface of the scaffold, chemotransportation is not guaranteed within the porous confines of the scaffold interior. (b) Schematic chamber within the flow-perfusion bioreactor. Note that medium is forced to percolate through the scaffold interior, ensuring chemotransportation to cells within the core. (c) Schematic of the 8-chamber flow-perfusion bioreactor within a standard cell culture incubator. (d) Photograph.
