Cytotoxic Effect of Recombinant Mycobacterium tuberculosis CFP-10/ESAT-6 Protein on the Crucial Pathways of WI-38 Cells

Figure 5

Inferred model for the rCFES-regulated focal adhesion pathway in WI-38 cells. LAMA4, PIK3R3, BIRC3, and NFKBIA identified in this study were included in the rCFES-regulated model in WI-38 cells. Upregulated genes were marked by “↑” and downregulated genes by “⟂”. Dotted arrows were links requiring further confirmation and the numbers in “[]” were the supportive previous works listed in the reference.