A New Caspase-8 Isoform Caspase-8s Increased Sensitivity to Apoptosis in Jurkat Cells
The cDNA and protein sequences of the novel isoform of caspase-8 (caspase-8s). (a) The sequence from start codon ATG to stop codon TAG of caspase-8s comparing with caspase-8. the sequence underlined is the deletion region. (b) The protein sequence of caspase-8 and caspase-8s. (c) Scheme illustrates that the deletion may result in the termination of the transcript in advance with the predicted generation of 108 aa protein.
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