Monocyte Chemoattractant Protein-1− 2518 A/G Single Nucleotide Polymorphism Might Be Associated with Renal Disease and Thrombocytopenia of SLE

Table 2

Association of the MCP-1 –2518 A>G polymorphisms in SLE patients and controls.

MCP-1 –2518 A>G (rs1024611)	SLE 𝑛=199 (%)	Controls 𝑛=250 (%)	OR	95%CI	(d)P-value
Genotype frequency
A/A	103 (51.8)	125 (50.0)
A/G	80 (40.2)	102 (40.8)
G/G	16 (8.0)	23 (9.2)	0.8629(a)	0.4428–1.682	0.6647
A/G+ G/G	96 (48.2)	125 (50.0)	0.9320(b)	0.6421–1.353	0.7111
Allele frequency
A	286 (71.9)	352 (70.4)
G	112 (28.1)	148 (29.6)	0.9314(c)	0.6963–1.246	0.6320

The Odds ratio was calculated for patients (a)(G/G genotype versus A/G and A/A genotypes); (b)(G/G and A/G genotype versus A/A genotype).
We also determined the OR for the patients’ minor allele (c)(G versus A allele); (d)uncorrected Chi².