Review Article

Dielectrophoresis: A Review of Applications for Stem Cell Research

Figure 3

The cytoplasmic membrane exhibits an electrical capacitance, whose value per unit membrane area is proportional to such structural features as membrane folding, microvilli, and blebs, for example. As indicated in this theoretical modelling, and demonstrated experimentally [46], changes in membrane surface features result in a shift of the DEP cross-over frequency 𝑓 x o 1 . The example shown here, for typical membrane capacitance values, demonstrates the change expected for a doubling of the effective surface “roughness” of the membrane.