Research Article

Extraction and Purification of a Lectin from Red Kidney Bean and Preliminary Immune Function Studies of the Lectin and Four Chinese Herbal Polysaccharides

Table 3

Effects of concurrent application of APS and red kidney bean lectin on the spleen and thymus indices and phagocytosis of 𝑀 Φ of mouse. Data represent means ± SD ( 𝑛 = 1 0 ).

groupSpleen index
(mg/g/bw)
Thymus index
(mg/g/bw)
Phagocytic
index 𝛼 of 𝑀 Φ

Control 4 . 7 1 ± 0 . 6 5 2 . 0 6 ± 0 . 4 5 4 . 0 6 ± 0 . 8 2
Lectin control 4 . 7 5 ± 0 . 9 0 2 . 0 6 ± 0 . 5 3 4 . 4 7 ± 1 . 1 1
APS 5 . 0 0 ± 0 . 8 0 2 . 1 5 ± 0 . 6 1 5 . 3 3 ± 1 . 4 2
Low dose 4 . 8 5 ± 0 . 6 5 2 . 1 9 ± 0 . 8 1 4 . 6 9 ± 0 . 9 3
Middle dose 5 . 4 6 ± 0 . 8 5 2 . 0 9 ± 0 . 4 3 5 . 4 2 ± 0 . 9 0
High dose 6 . 5 0 ± 1 . 0 4 2 . 2 8 ± 0 . 6 5 5 . 8 1 ± 1 . 3 8

APS: Astragalus Polysaccharides
Control: normal saline; Lectin group: 12.5 mg/kg/bw red kidney bean lectin; APS group: 100 mg/kg/bw APS; Low dose group: 12.5 mg/kg/bw lectin + 25 mg/kg/bw APS; Moderate dose group: 12.5 mg/kg/bw lectin + 50 mg/kg/bw APS; High dose group: 12.5 mg/kg/bw lectin + 100 mg/kg/bw APS. Data were analyzed by one-way analysis of variance. 𝑃 < . 0 5 , 𝑃 < . 0 1 , compared with the control group.