Research Article

Mouse Homologue of the Schizophrenia Susceptibility Gene ZNF804A as a Target of Hoxc8

Table 1

Candidate downstream targets of Hoxc8 from ChIP-cloning. Referred to Chung HJ et al. [10].

ACCN no.Gene nameNo. of Hox-binding motifsChromosomeLocationMolecular/cellular function

NM_175513zinc finger protein 804A752intron 1zinc ion binding; metal ion binding

NM_001085495ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited)222intron 1ARF guanyl-nucleotide exchange factor activity; binding; myosin binding; exocytosis; intracellular signaling cascade; regulation of ARF protein signal transduction

NW_001030820118.3 kb at 5 side: hypothetical proteinunknown
206intergenic region
XM_920612.2 22 kb at 3 side: Similar to lanin A-related sequence 1 protein isoform 2unknown

NM_028533.247 kb at 5 side: hypothetical protein LOC 73410unknown
209intergenic region
NM_011916.250 kb at 3 side: 5 - 3 exoribonuclease 1 5 - 3 exonuclease and hydrolase activities

NM_080788.3tau tubulin kinase 2 isoform 1,2162intron 10nucleotide binding; protein serine/threonine kinase activity; ATP binding; transferase activity

NM_153386.2Usher syndrome 3A homolg isoform 1,2133intron 1sensory perception of sound; photoreceptor cell maintenance; equilibrioception

NM_172964.3134 kb at 5 side: Rho GTPase activating protein 28GTPase activator activity
1117intergenic region
NM_177278.3221 kb at 3 side: hypothetical protein LOC320858unknown

NM_172825.2G protein-coupled receptor 1281016intron 4neuropeptide signaling pathway; G-protein coupled receptor activity

NM_001083919.1139 kb at 5 side: Cardiomyopathy associated 3 isoform 2unknown
102intergenic region
NM_020283.2459 kb at 3 side: UDP-Gal:βGlcNAc β1,3-galatosyl transferaseprotein amino acid glycosylation; oligosaccharide biosynthetic process; lipid glycosylation

NM_013600mutS homolog 5817intron 11nucleotide binding; DNA binding; protein binding; ATP binding; mismatched DNA binding; NF-kappaB binding

NM_008960.2phosphatase and tensin homolog419intron 5phosphatidylinositol-3-phosphatase activity; protein serine/threonine phosphatase activity; PDZ domain binding

NM_011796.2calpain 1001intron 5/exon 6SNARE binding; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; peptidase activity